Virest 400mg Tablet

INDICATIONS

Used for the systemic treatment of varicella-zoster (Chicken pox shingles) and the systemic and topical treatment of herpes simplex infections of the skin and mucous membranes.

DOSAGE AND ADMINISTRATION

Adults

Genital herpes infections

Initial therapy: Oral, 200 mg 5 times a day for 10 days.

• Creatinine clearance >10 ml/min: Oral, 200 mg 5 times a day for 10 days.

• Creatinine clearance 0-10 ml/min: Oral, 200 mg twice a day for 10 days.

Intermittent therapy: Oral, 200 mg 5 times a day for 5 days.

• Creatinine clearance >10 ml/min: Oral, 200 mg 5 times a day for 5 days.

• Creatinine clearance 0-10 ml/min: Oral, 200 mg twice a day for 5 days.

Chronic suppressive therapy: Oral, 400 mg twice a day; or 200 mg

2 to 5 times a day.

• Creatinine clearance >10 ml/min: Oral, 400 mg twice a day.

• Creatinine clearance 0-10 ml/min: Oral, 200 mg twice a day.

Herpes zoster

Oral, 800 mg 5 times a day for 7 to 10 days.

Creatinine clearance >25 ml/min: 800 mg 5 times a day for 7 to 10 days.

Creatinine clearance 10-25 ml/min: 800 mg 3 times a day for 7 to 10 days.

Creatinine clearance 0-10 ml/min: 800 mg twice a day for 7 to 10 days.

Varicella

Oral, 20 mg per kg of body weight, up to 800 mg per dose, 4 times a day for 5 days. Treatment should be initiated at the earliest sign or symptoms of chickenpox

Herpes simplex

Oral, 200 to 400 mg 5 times a day for 10 days in immunocompromised patients.

Paediatrics

Children < 2 years:

Dosage has not been established in children up to 2 years of age. However, no unusual toxicity or paediatric-specific problems have been observed in studies done in children using doses of up to

3000 mg/m2/day and 80 mg/kg/day.

Children 2 to 12 years:

Varicella: Oral 20 mg per kg of body weight, up to 800 mg per dose, 4 times a day for 5 days. Treatment should be initiated at the earliest sign or symptom of chickenpox

Caution: Food, Drugs, Devices & Cosmetics Act prohibits dispensing without prescription.

Note: The information given here is limited. For further information, kindly consult your doctor or pharmacist.

Caution: Foods, Drugs, Devices and Cosmetics Act prohibits dispensing without prescription.