Hovizol 20mg

INDICATIONS

Omeprazole is indicated for:

• treatment of reflux oesophagitis.

• duodenal ulcer; benign gastric ulcer.

• long term treatment of pathologic gastric hypersecretion associated with Zollinger-Ellison syndrome.

DOSAGE AND ADMINISTRATION

Omeprazole (Hovizol) capsules are recommended to be taken immediately before meals, preferably in the morning and swallowed whole with liquid. For patients with swallowing difficulties the capsule might be opened and the contents swallowed or suspended in a slightly acidic fluid e.g juice, soured milk, or non-carbonated water. The dispersion should be taken immediately or within 30 minutes. Alternatively, patients can suck the capsule and swallow the pellets with liquid. The pellets must not be chewed or crushed.

Usual adult and adolescent dose:

• Reflux Oesophagitis: The recommended dosage is Omeprazole 20 mg once daily. Symptom resolution is rapid, and, in most patients, healing occurs within 4 weeks. For those patients who may not be fully healed after the initial course, healing usually occurs during a further 4 weeks treatment period. In patients with severe reflux oesophagitis, Omeprazole 40 mg once daily is recommended, and healing is usually achieved within 8 weeks.

• Duodenal Ulcer/ Benign Gastric Ulcer: Oral, 20 mg once a day. The dosage can be increased to 40 mg once a day for duodenal/gastric ulcer refractory to other treatment regimens. If healing of gastric ulcer has not occurred within 4 weeks, an additional 4 weeks of treatment is recommended. Long term therapy for patients with history of recurrent duodenal ulcer is recommended at a dosage of 20 mg Omeprazole once daily, up to one year.

• Gastric hypersecretory (e.g., Zollinger-Ellison): Oral, 60 mg once a day, the dosage being adjusted as needed, and therapy continued for as long as clinically indicated.

• Dose adjustment is not required in the elderly.

• Impaired renal function: Dose adjustment is not required in patients with impaired renal function.

• Impaired hepatic function: As bioavailability and plasma half-life of omeprazole are increased in patients with impaired hepatic function, a daily dose of 20 mg may be sufficient.

Note: The information given here is limited. For further information, kindly consult your doctor or pharmacist.

Caution: Foods, Drugs, Devices and Cosmetics Act prohibits dispensing without prescription.